It is estimated that one third of the American population is obese, a condition which is a serious risk factor for many diseases. Exciting findings indicate possibly using a natural plant supplement in the treatment of obesity. Extracts from the rind of the fruit-bearing Garcinia cambugia, commonly known as Malabar tamarind and found in southern Asia, has been researched for its weight loss properties. The results offer a great deal of hope.
The fruit's main property, hydroxycitric acid (HCA), is similar to citric acid. HCA promotes weight loss in several ways. It reduces the amount of stored body fat by binding to, and therefore inhibiting, the enzyme ATP-citrate lyase. This enzyme is involved in storing excess energy as fat, when more calories have been consumed than the body's energy demands require. Another advantage of HCA binding to this enzyme is the partnership reduces the production of acetyl coenzyme A, which in turn promotes more efficient glycogen use by the liver. This results in a heightened feeling of fullness and decreased appetite. Unlike many over-the-counter appetite suppressants, HCA does not directly effect the central nervous system or brain. It therefore does not induce the unpleasant side effects of these other products such as depression, insomnia, hypertension, or rapid heart beat. The body is also unlikely to develop a tolerance to HCA.
Research findings indicate HCA to be safe and effective. A study conducted in 1991 found obese subjects on a program of HCA, niacin-bound chromium, and calorie restriction lost an average of eleven pounds in two weeks, while subjects taking placebos lost an average of four pounds during this time. Another study on rats found a decrease in fat storage and cholesterol production in the liver only 150 minutes after HCA was administered. HCA appears to be a promising adjunct to a weight loss program of sensible eating and exercise.
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