Glucosamine sulfate appears to be a viable treatment for osteoarthritis. Traditionally, this disease has been treated with pain relievers and anti-inflammatories like aspirin and NSAIDS (nonsteroidal anti-inflammation drugs) such as ibuprofen. While these drugs relieve the symptoms of osteoarthritis, they can actually worsen the condition because it actually promotes progression of the disease process by inhibiting cartilage glycosaminoglycan (GAG) synthesis and cartilage repair.
The advantage of glucosamine sulfate is that it not only relieves the pain associated with arthritis, but also promotes reparation of the joint damage by providing the building block for GAG. Glucosamine sulfate is a natural substance found within the joints that sparks the production of cartilage and admits sulfur into cartilage tissue for joint repair. So it not only helps generate substances necessary for proper joint function, it also is responsible for stimulating joint repair. It appears that the sulfur component is critical to the success of glucosamine sulfate in joint repair. Sulfur is an essential nutrient for joint tissue where it functions in the stabilization of the connective tissue matrix of ligaments, tendons and cartilage.
The body's ability to make glucosamine generally declines as we age. A standard dose of this supplement is 500 mg three times per day, though heavier individuals may require more. There appear to be no contra-indications or adverse interactions with drugs. If gastrointestinal upset occurs, it is recommended to take glucosamine sulfate with food.
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